Police investigating the murder of a nurse found brutally beaten to death in her family home 25 years ago have made a fresh appeal for information in a bid to finally bring her killer to justice.Janet Brown, 51, was found at the foot of the stairs with fatal, blunt-force head injuries on April 10 1995 at her home in the quiet village of Radnage in Buckinghamshire.The mother-of-three was naked, with her arms handcuffed behind her back and her mouth gagged with packing tape.The victim had suffered four or five blows to the head from a weapon such as a crowbar.Nothing was taken from the detached house on Sprigs Holly Lane and although Mrs Brown was found naked, there was no evidence she had been sexually assaulted.The method of entry has also confused police, with the killer trying to cut a man-sized hole out of a double-glazed patio door using a glass cutter – an incredibly time-consuming and difficult process. Eventually, they just smashed their way through.